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William G. Kraybill, Jonathan Harris, Ira J. Spiro, David S. Ettinger, Thomas F. DeLaney, Ronald H. Blum, David R. Lucas, David C. Harmon, G. Douglas Letson and Burton Eisenberg Long-term results of a phase 2 study of neoadjuvant chemotherapy and radiotherapy in the management of high-risk, high-grade, soft tissue sarcomas of the extremities and body wall Cancer 116

Version of Record online: 19 AUG 2010 | DOI: 10.1002/cncr.25350

Sixty-four patients were managed with neoadjuvant mesna, doxorubicin, ifosfamide, and dacarbazine chemotherapy; radiation; resection; and adjuvant mesna, doxorubicin, ifosfamide, and dacarbazine chemotherapy for advanced high-grade extremity and torso soft tissue sarcomas. Although toxic, this long-term analysis demonstrates results somewhat better than might be expected for such high-risk tumors.

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