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Thomas Yau, Pierre Chan, Roberta Pang, Kelvin Ng, S. T. Fan and Ronnie T. Poon Phase 1-2 trial of PTK787/ZK222584 combined with intravenous doxorubicin for treatment of patients with advanced hepatocellular carcinoma Cancer 116

Article first published online: 13 JUL 2010 | DOI: 10.1002/cncr.25372

The combination of PTK787 and doxorubicin shows encouraging activity in advanced hepatocellular carcinoma patients. Thus, the idea of combining an antiangiogenic agent together with chemotherapy warrants further evaluation in future clinical trials.

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