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Motofumi Tanaka, Taro Okazaki, Hideo Suzuki, James L. Abbruzzese and Donghui Li Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome Cancer 117

Version of Record online: 4 OCT 2010 | DOI: 10.1002/cncr.25510

In this study, we demonstrated that polymorphic variants of drug resistance genes MRP5 and MRP2 are associated with tumor response to gemcitabine-based chemoradiotherapy and overall survival in patients with potentially resectable pancreatic cancer. This information has the potential to help with treatment selection for individualized therapy of pancreatic cancer.

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