Diana Bell, Dianna Roberts, Merrill Kies, Pulivarthi Rao, Randal S. Weber and Adel K. El-Naggar Cell type-dependent biomarker expression in adenoid cystic carcinoma Cancer 116
Article first published online: 7 SEP 2010 | DOI: 10.1002/cncr.25541
The authors of this report hypothesized that the dual cellular composition of adenoid cystic carcinoma (ACC) plays an important role in biomarker evaluation, tumor biologic behavior, and response to therapy. The current findings underscored the importance of accessing the differential localizations of different biomarkers in myoepithelial and ductal cells of ACC in the biologic evaluations and therapeutic stratification of this entity.
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