Harvey J. Mamon, Donna Niedzwiecki, Donna Hollis, Benjamin R. Tan, Robert J. Mayer, Joel E. Tepper, Richard M. Goldberg, A. William Blackstock, Charles S. Fuchs and for the Cancer and Leukemia Group B A phase 2 trial of gemcitabine, 5-fluorouracil, and radiation therapy in locally advanced nonmetastatic pancreatic adenocarcinoma Cancer 117
Version of Record online: 23 DEC 2010 | DOI: 10.1002/cncr.25742
This phase 2 cooperative group trial combined 2 types of radiosensitizing chemotherapy, 5-fluorouracil and gemcitabine, with external beam radiation therapy in the treatment of patients with locally advanced pancreatic cancer. The regimen was well tolerated, with a median time to progression of 10 months and a median overall survival of 12.2 months.
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