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Sumit Gupta, Federico A. Antillon, Miguel Bonilla, Ligia Fu, Scott C. Howard, Raul C. Ribeiro and Lillian Sung Treatment-related mortality in children with acute lymphoblastic leukemia in Central America Cancer 117

Version of Record online: 28 MAR 2011 | DOI: 10.1002/cncr.26107

Rates of treatment-related mortality (TRM) were significantly higher in patients with acute lymphoblastic leukemia (ALL) in low-income countries compared with similar patients in high-income countries. In a cohort of children with ALL across 3 Central American countries, the authors observed that the timing, causes, and predictors of TRM were different in this population than in high-income settings, suggesting that different interventions are required to improve outcomes.

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