Jeannelyn S. Estrella, Asif Rashid, Jason B. Fleming, Matthew H. Katz, Jeffrey E. Lee, Robert A. Wolf, Gauri R. Varadhachary, Peter W. T. Pisters, Eddie K. Abdalla, Jean-Nicolas Vauthey, Hua Wang, Henry F. Gomez, Douglas B. Evans, James L. Abbruzzese and Huamin Wang Post-therapy pathologic stage and survival in patients with pancreatic ductal adenocarcinoma treated with neoadjuvant chemoradiation Cancer 118
Article first published online: 6 JUL 2011 | DOI: 10.1002/cncr.26243
The authors demonstrated that post-therapy pathologic American Joint Committee on Cancer stage and the number of positive lymph nodes were independent prognostic factors for both disease-free and overall survival in a consecutive cohort of 240 patients with pancreatic ductal adenocarcinoma (PDAC) who received neoadjuvant chemoradiation followed by pancreaticoduodenectomy (PD). Pathologic evaluation of PD specimen and post-therapy pathologic tumor staging remained the key factors in predicting clinical outcome in patients with PDAC who received neoadjuvant chemoradiation and subsequent PD.
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