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Iris Cordoba, José R. González-Porras, Benet Nomdedeu, Elisa Luño, Raquel de Paz, Esperanza Such, Mar Tormo, Teresa Vallespi, Rosa Collado, Blanca Xicoy, Rafael Andreu, Juan A. Muñoz, Francesc Solé, Jose Cervera, Consuelo del Cañizo and On behalf of the Spanish Myelodysplastic Syndrome Registry Better prognosis for patients with del(7q) than for patients with monosomy 7 in myelodysplastic syndrome Cancer 118

Version of Record online: 29 JUN 2011 | DOI: 10.1002/cncr.26279

Abnormalities involving chromosome 7 are frequent in myelodysplastic syndrome (MDS) and suggest a poor prognosis. In this study, the authors observed that isolated patients who had MDS with deletion of part of the long arm of chromosome (7q) had distinct clinicopathologic characteristics and better survival than patients who had MDS with isolated monosomy 7 (complete loss of chromosome 7). Therefore, the current results indicate that isolated 7q deletion no longer should be considered in the same prognostic category as monosomy 7.

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