Niklas Thon, Sabina Eigenbrod, Simone Kreth, Juergen Lutz, Joerg-Christian Tonn, Hans Kretzschmar, Aurelia Peraud and Friedrich-Wilhelm Kreth IDH1 mutations in grade II astrocytomas are associated with unfavorable progression-free survival and prolonged postrecurrence survival Cancer 118
Article first published online: 29 JUN 2011 | DOI: 10.1002/cncr.26298
In World Health Organization grade II astrocytomas, IDH1 mutations exhibit Janus headlike properties; an as yet unknown unfavorable prognostic influence on progression-free survival turns into a favorable impact after malignant transformation.
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