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Abha A. Gupta, James R. Anderson, Alberto S. Pappo, Sheri L. Spunt, Roshni Dasgupta, Daniel J. Indelicato and Douglas S. Hawkins Patterns of chemotherapy-induced toxicities in younger children and adolescents with rhabdomyosarcoma Cancer 118

Version of Record online: 14 JUL 2011 | DOI: 10.1002/cncr.26358

Adolescents with rhabdomyosarcoma experienced less hematologic toxicity and greater peripheral nervous system toxicity compared with younger children. Females, regardless of age, experienced more hematologic toxicity than males. Future studies examining the age-related and sex-related differences in pharmacokinetics of chemotherapy are necessary.

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