Kunal C. Kadakia, Debra L. Barton, Charles L. Loprinzi, Jeff A. Sloan, Clark C. Otley, Brent B. Diekmann, Paul J. Novotny, Steven R. Alberts, Paul J. Limburg and Mark R. Pittelkow Randomized controlled trial of acitretin versus placebo in patients at high-risk for basal cell or squamous cell carcinoma of the skin (North Central Cancer Treatment Group Study 969251) Cancer 118
Version of Record online: 31 AUG 2011 | DOI: 10.1002/cncr.26374
In this randomized, double-blind, chemoprevention trial, the authors demonstrate that the use of acitretin fails to significantly reduce the incidence or the time to first new nonmelanoma skin cancer in nontransplantation patients with 2 or more previous nonmelanoma skin cancers.
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