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Dirk Rades, Theo Veninga, Dagmar Hornung, Oliver Wittkugel, Steven E. Schild and Jan Gliemroth Single brain metastasis: whole-brain irradiation plus either radiosurgery or neurosurgical resection Cancer 118

Version of Record online: 14 JUL 2011 | DOI: 10.1002/cncr.26379

This study compared neurosurgical resection followed by whole-brain irradiation (WBI) with WBI followed by radiosurgery (WBI + RS) in 152 patients with a single brain metastasis. The less invasive regimen of WBI + RS resulted in significantly better local control of the treated metastasis, whereas survival was not found to be significantly different in both groups.

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