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Joseph M. Letourneau, Erin E. Ebbel, Patricia P. Katz, Kutluk H. Oktay, Charles E. McCulloch, Wei Z. Ai, A. Jo Chien, Michelle E. Melisko, Marcelle I. Cedars and Mitchell P. Rosen Acute ovarian failure underestimates age-specific reproductive impairment for young women undergoing chemotherapy for cancer Cancer 118

Article first published online: 17 AUG 2011 | DOI: 10.1002/cncr.26403

The authors demonstrate that rates of acute ovarian failure alone underestimate the effect of chemotherapy on reproductive function in women of reproductive age. To give patients appropriate, age-specific counseling, it is critical that they understand the increased risk of infertility and early menopause beyond that of acute ovarian failure.

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