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Corey J. Langer Exploring biomarkers in head and neck cancer Cancer 118

Version of Record online: 26 JAN 2012 | DOI: 10.1002/cncr.26718

Biomarker research in squamous cell carcinoma of the head and neck (SCCHN) has produced recent advances; certain markers, such as ERCC1 and RRM1, may help refine the use of chemotherapy, and human papillomavirus status defines a distinct subtype of oropharyngeal disease with better prognosis. However, there are no prospectively validated markers for epidermal growth factor receptor-targeted therapies in SCCHN or for conventional cytotoxic agents.

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