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Nelli Bejanyan, Ramon V. Tiu, Azra Raza, Ania Jankowska, Matt Kalaycio, Anjali Advani, Josephine Chan, Yogen Saunthararajah, Lindsey Mooney, Jaroslaw P. Maciejewski and Mikkael A. Sekeres A phase 2 trial of combination therapy with thalidomide, arsenic trioxide, dexamethasone, and ascorbic acid (TADA) in patients with overlap myelodysplastic/myeloproliferative neoplasms (MDS/MPN) or primary myelofibrosis (PMF) Cancer 118

Article first published online: 16 DEC 2011 | DOI: 10.1002/cncr.26741

The thalidomide, arsenic trioxide, dexamethasone, and ascorbic acid (TADA) regimen yields clinical responses in patients with primary myelofibrosis and myelodysplastic/myeloproliferative neoplasms. It is reasonable to incorporate multiple novel agents in these rare diseases.

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