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Shaheenah Dawood, Xiudong Lei, Jennifer K. Litton, Thomas A. Buchholz, Gabriel N. Hortobagyi and Ana M. Gonzalez-Angulo Incidence of brain metastases as a first site of recurrence among women with triple receptor–negative breast cancer Cancer 118
Article first published online: 22 FEB 2012 | DOI: 10.1002/cncr.27434
Patients with nonmetastatic triple receptor–negative (negative for estrogen receptor, progesterone receptor, and HER2/neu) breast cancer have a high early incidence of developing brain metastases as a first site of recurrence, which is associated with subsequent poor survival. Patients with stage III triple receptor–negative breast cancer in particular would be an ideal cohort in which to research preventive strategies.
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