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Jeffrey Peppercorn, Iuliana Shapira, Teressa Deshields, Deanna Kroetz, Paula Friedman, Patricia Spears, Deborah E. Collyar, Lawrence N. Shulman, Lynn Dressler and Monica M. Bertagnolli Ethical aspects of participation in the Database of Genotypes and Phenotypes of the National Center for Biotechnology Information Cancer 118

Article first published online: 13 MAR 2012 | DOI: 10.1002/cncr.27515

The rapid pace of genetics research, coupled with evolving standards for informed consent, can create ethical challenges regarding future use of tissue or information from completed clinical trials. Although modern standards for informed consent should not prohibit research or sharing of data consistent with participants' intent and the public interest, there is an urgent need for national consensus on the appropriate use of archived tissue and standardized informed consent for future research among cancer clinical trial participants.

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