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Fang Nie, Jian Yang, Song Wen, Yan-Li An, Jie Ding, Sheng-Hong Ju, Zhen Zhao, Hua-Jun Chen, Xin-Gui Peng, Stephen T. C. Wong, Hong Zhao and Gao-Jun Teng Involvement of epidermal growth factor receptor overexpression in the promotion of breast cancer brain metastasis Cancer 118

Version of Record online: 17 APR 2012 | DOI: 10.1002/cncr.27553

Epidermal growth factor receptor (EGFR) plays more important roles in cell migration and invasion to the brain than it plays in cell proliferation progression in breast cancer brain-seeking cells. The current findings provide new evidence of the potential value of EGFR inhibition in treating brain-metastatic breast cancer.

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