Alfonso Quintás-Cardama, Yi Hua Qiu, Sean M. Post, Yiqun Zhang, Chad J. Creighton, Jorge Cortes and Steven M. Kornblau Reverse phase protein array profiling reveals distinct proteomic signatures associated with chronic myeloid leukemia progression and with chronic phase in the CD34-positive compartment Cancer 118
Version of Record online: 19 APR 2012 | DOI: 10.1002/cncr.27568
Reverse phase protein array profiling defines a specific set of proteins associated with the transformation from chronic phase to advanced phase chronic myeloid leukemia (CML). Some of these proteins also are overexpressed in CML stem cells. These results may unveil important targets to pharmacologically eradicate minimal residual disease in CML.
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