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Ruth Etzioni, Roman Gulati, Alex Tsodikov, Elisabeth M. Wever, David F. Penson, Eveline A.M. Heijnsdijk, Jeffrey Katcher, Gerrit Draisma, Eric J. Feuer, Harry J. de Koning and Angela B. Mariotto The prostate cancer conundrum revisited Cancer 118

Version of Record online: 17 MAY 2012 | DOI: 10.1002/cncr.27594

Three models of prostate cancer natural history are combined with data on patterns of primary treatment, including hormone therapies and trial-based estimates of treatment efficacy. The results indicate that changes in these treatments explain 22% to 33% of the observed decline in prostate cancer mortality between 1991 and 2005.

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