Shengxiang Ren, Xiaoxia Chen, Peng Kuang, Limou Zheng, Chunxia Su, Jiayu Li, Bing Li, Yongshen Wang, Lu Liu, Qiong Hu, Jie Zhang, Liang Tang, Xuefei Li, Caicun Zhou and Gerald Schmid-Bindert Association of EGFR mutation or ALK rearrangement with expression of DNA repair and synthesis genes in never-smoker women with pulmonary adenocarcinoma Cancer 118
Article first published online: 8 MAY 2012 | DOI: 10.1002/cncr.27603
Nonsmall cell lung cancer specimens that harbor activating epidermal growth factor receptor (EGFR) mutations are more likely to express low excision repair cross-complementing 1 (ERCC1) and thymidylate synthetase mRNA levels, whereas patients with nonsmall cell lung cancer who have an anaplastic lymphoma kinase (ALK) rearrangement are more likely to express low thymidylate synthetase mRNA levels.
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