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Xiao-Xiao Lu, Jiang-Liu Yu, Li-Sha Ying, Jing Han, Shi Wang, Qi-Ming Yu, Xin-Bao Wang, Xian-Hua Fang and Zhi-Qiang Ling Stepwise cumulation of RUNX3 methylation mediated by Helicobacter pylori infection contributes to gastric carcinoma progression Cancer 118

Version of Record online: 10 MAY 2012 | DOI: 10.1002/cncr.27604

Runt-related transcription factor 3 (RUNX3) methylation is a risk factor for the carcinogenesis of chronic atrophic gastritis with Helicobacter pylori infection. Circulating RUNX3 methylation is a valuable biomarker for the detection of early gastric cancer.

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