Meredith S. Shiels, Eric A. Engels, Jianxin Shi, Maria Teresa Landi, Demetrius Albanes, Nilanjan Chatterjee, Stephen J. Chanock, Neil E. Caporaso and Anil K. Chaturvedi Genetic variation in innate immunity and inflammation pathways associated with lung cancer risk Cancer 118
Version of Record online: 8 OCT 2012 | DOI: 10.1002/cncr.27605
The authors conduct a broad evaluation of the association of single nucleotide polymorphisms (SNPs) in innate immunity and inflammation pathways with lung cancer risk and compare their results with a lung cancer genome-wide association study (GWAS). A significant association is observed between a variant in the NFKB1 gene and the risk of lung cancer.
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