Tobias Klatte, Nils Kroeger, Edward N. Rampersaud, Frédéric D. Birkhäuser, Joshua E. Logan, Geoffrey Sonn, Joseph Riss, P. Nagesh Rao, Fairooz F. Kabbinavar, Arie S. Belldegrun and Allan J. Pantuck Gain of chromosome 8q is associated with metastases and poor survival of patients with clear cell renal cell carcinoma Cancer 118
Version of Record online: 17 MAY 2012 | DOI: 10.1002/cncr.27607
Gain of chromosome 8q is associated with an increased risk of metastases and death from clear cell renal cell carcinoma. Defining tumors with gain of 8q may assist in identifying patients for specific c-MYC inhibitors or agents targeting the MAPK/ERK pathway.
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