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Paul K. Paik, Melissa L. Johnson, Sandra P. D'Angelo, Camelia S. Sima, Daphne Ang, Snjezana Dogan, Vincent A. Miller, Marc Ladanyi, Mark G. Kris and Gregory J. Riely Driver mutations determine survival in smokers and never-smokers with stage IIIB/IV lung adenocarcinomas Cancer 118

Article first published online: 17 MAY 2012 | DOI: 10.1002/cncr.27637

The median overall survival of never-smokers with advanced lung adenocarcinomas is significantly higher than that of smokers. The authors present data indicating that distinct mutation profiles in each subgroup drive the smoking-related prognostic differences that have been observed.

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