Travis J. Yates, Judith Knapp, Miguel Gosalbez, Soum D. Lokeshwar, Christopher S. Gomez, Anaid Benitez, Obi O. Ekwenna, Ezekiel E. Young, Murugesan Manoharan and Vinata B. Lokeshwar C-X-C chemokine receptor 7 Cancer 119
Article first published online: 26 JUN 2012 | DOI: 10.1002/cncr.27661
This is the first study that shows C-X-C chemokine receptor 7 (CXCR7) expression is elevated in bladder cancer tissues and exfoliated urothelial cells and correlates with aggressive phenotype with high accuracy. CXCR7 promotes bladder cancer cell proliferation, motility, and survival, plausibly through epidermal growth factor receptor and/or Akt signaling.
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