Ulrich Güller, Andreas Zettl, Mathias Worni, Igor Langer, Daniela Cabalzar-Wondberg, Carsten T. Viehl, Nicolas Demartines and Markus Zuber Molecular investigation of lymph nodes in colon cancer patients using one-step nucleic acid amplification (OSNA) Cancer 118
Article first published online: 8 JUN 2012 | DOI: 10.1002/cncr.27667
The authors assessed 313 lymph nodes from consecutive patients with colon cancer using one-step nucleic acid amplification (OSNA). OSNA is a powerful molecular tool for the detection of lymph node metastases in patients with colon cancer and has improved performance compared with standard hematoxylin and eosin analysis.
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