Hye Won Chung, Sunphil Jang and Jong-Baeck Lim Clinical implications and diagnostic usefulness of correlation between soluble major histocompatibility complex class I chain-related molecule a and protumorigenic cytokines in pancreatic ductal adenocarcinoma Cancer 119
Article first published online: 26 JUN 2012 | DOI: 10.1002/cncr.27669
Soluble major histocompatibility complex class I chain-related molecule A (sMICA) may be involved in tumor-associated angiogenesis and tumor growth by affecting corresponding cytokines as well as causing impairment of natural killer cell cytotoxicity in the development and progression of pancreatic ductal adenocarcinoma (PDAC). The results of this study will provide valuable information to develop new soluble biomarkers or therapeutic approaches in PDAC with respect to sMICA and dysregulated cytokines in PDAC.
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