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Isabelle Etienney, Sarra Vuong, Ali Si-Mohamed, Jean-François Fléjou, Patrick Atienza, Pierre Bauer and and the Cytological Diaconesses Group Value of cytologic Papanicolaou smears and polymerase chain reaction screening for human papillomavirus DNA in detecting anal intraepithelial neoplasia Cancer 118

Article first published online: 6 JUN 2012 | DOI: 10.1002/cncr.27671

Compared with a large surgical sample, anal cytologic Papanicolaou smears and human papillomavirus polymerase chain reaction exhibited varied sensitivity and specificity according to the risk of human papillomavirus infection and anal intraepithelial neoplasia. This study explores the potential of these examinations as screening strategies for precancerous anal lesions based on the population at risk.

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