Sue C. Kaste, Samuel L. Brady, Brian Yee, Valerie J. McPherson, Robert A. Kaufman, Catherine A. Billups, Najat C. Daw and Alberto S. Pappo Is routine pelvic surveillance imaging necessary in patients with Wilms tumor? Cancer 119
Article first published online: 26 JUN 2012 | DOI: 10.1002/cncr.27687
Omitting pelvic computed tomography from the routine, off-therapy follow-up of patients with Wilms tumor saves an average 30% to 45% of the effective dose (when imaging at a 120-kilovolt peak) without compromising disease detection. The use of this modality in patients with high-risk features for pelvic recurrence or pelvic disease, such as age at diagnosis ≥48 months, higher stage disease (stage III), specimen weight >1000 g, positive tumor margins, capsular penetration, tumor spillage, or unfavorable histology, deserves investigation in prospective national clinical trials.
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