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Emmanuel S. Antonarakis, Daniel Keizman, Zhe Zhang, Bora Gurel, Tamara L. Lotan, Jessica L. Hicks, Helen L. Fedor, Michael A. Carducci, Angelo M. De Marzo and Mario A. Eisenberger An immunohistochemical signature comprising PTEN, MYC, and Ki67 predicts progression in prostate cancer patients receiving adjuvant docetaxel after prostatectomy Cancer 118

Version of Record online: 6 JUN 2012 | DOI: 10.1002/cncr.27689

The authors previously conducted a prospective study evaluating adjuvant docetaxel chemotherapy in men with high-risk localized prostate cancer undergoing radical prostatectomy. After performing immunohistochemical analysis on formalin-fixed, paraffin-embedded tissues from the resected prostate glands of these men, the authors now report that PTEN status, MYC expression, and Ki67 expression are useful predictors of progression in this patient population.

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