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Tao Li, Lun-Xiu Qin, Xiao Gong, Jian Zhou, Hui-Chuan Sun, Shuang-Jian Qiu, Qing-Hai Ye, Lu Wang and Jia Fan Hepatitis B virus surface antigen-negative and hepatitis C virus antibody-negative hepatocellular carcinoma Cancer 119

Version of Record online: 26 JUN 2012 | DOI: 10.1002/cncr.27697

Patients with hepatitis B virus surface antigen (HBsAg)-negative/hepatitis C virus antibody (HCVAb)-negative hepatocellular carcinoma (NBNC-HCC) have clinicopathologic characteristics and prognostic factors that differ from those in patients with HBsAg-positive/HCVAb-negative HCC. Compared with men, women who have NBNC-HCC have a poorer prognosis, and it may be worthwhile to evaluate estrogen administration for the maintenance of sex hormone balance and to improve these poor outcomes.

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