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Hao Xie, Wei Jiang, John Jiang, Yixin Wang, Richard Kim, Xiaobo Liu and Xiuli Liu Predictive and prognostic roles of ribonucleotide reductase M1 in resectable pancreatic adenocarcinoma Cancer 119

Version of Record online: 26 JUN 2012 | DOI: 10.1002/cncr.27715

Predictive factors of adjuvant therapy are lacking in patients with resectable pancreatic adenocarcinoma. Evaluation of the predictive value of ribonucleotide reductase M1 (RRM1) expression in this study demonstrates that low expression of RRM1 predicts gemcitabine treatment effect and that high expression of RRM1 predicts nongemcitabine treatment effect (mainly chemoradiation).

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