Tait D. Shanafelt, Timothy G. Call, Clive S. Zent, Jose F. Leis, Betsy LaPlant, Deborah A. Bowen, Michelle Roos, Kristina Laumann, Asish K. Ghosh, Connie Lesnick, Mao-Jung Lee, Chung S. Yang, Diane F. Jelinek, Charles Erlichman and Neil E. Kay Phase 2 trial of daily, oral polyphenon E in patients with asymptomatic, Rai stage 0 to II chronic lymphocytic leukemia Cancer 119
Version of Record online: 3 JUL 2012 | DOI: 10.1002/cncr.27719
In this phase 2 trial, daily oral use of the green tea extract epigallocatechin gallate in the Polyphenon E preparation was found to be well tolerated by patients with chronic lymphocytic leukemia. Durable declines in the absolute lymphocyte count and/or lymphadenopathy were observed in the majority of patients.
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