Anne Nguyen Kovochich, Michael Arensman, Anna R. Lay, Nagesh P. Rao, Timothy Donahue, Xinmin Li, Samuel W. French and David W. Dawson HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma Cancer 119
Article first published online: 22 AUG 2012 | DOI: 10.1002/cncr.27725
The homeobox B7 (HOXB7) gene is frequently overexpressed in pancreatic adenocarcinoma, in which it promotes an invasive phenotype and is associated with lymph node metastasis and poor survival. HOXB7 or its downstream targets represent potential clinical biomarkers or therapeutic targets in those cancers in which it is deregulated.
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