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Kristina R. Dahlstrom, Gabriel Calzada, Jennifer D. Hanby, Adam S. Garden, Bonnie S. Glisson, Guojun Li, Dianna B. Roberts, Randal S. Weber and Erich M. Sturgis An evolution in demographics, treatment, and outcomes of oropharyngeal cancer at a major cancer center Cancer 119

Article first published online: 26 JUN 2012 | DOI: 10.1002/cncr.27727

The overall survival of patients with squamous cell carcinoma of the oropharynx has improved significantly over the past 5 decades. Tumor classification and lymph node status are the most important factors for patients who were diagnosed between 1955 and 1994; and smoking status, T classification, age, and tumor site are the most important factors for patients who were diagnosed between 1995 and 2004. The current TNM staging system does not adequately predict survival in the 1995 to 2004 cohort and indicates the need to incorporate other factors, such as smoking and human papillomavirus status, into the staging system.

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