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Douglas Adkins, Jessica Ley, Kathryn Trinkaus, Wade Thorstad, James Lewis Jr, Tanya Wildes, Barry A. Siegel, Farrokh Dehdashti, Hiram Gay, Paul Mehan and Brian Nussenbaum A phase 2 trial of induction nab-paclitaxel and cetuximab given with cisplatin and 5-fluorouracil followed by concurrent cisplatin and radiation for locally advanced squamous cell carcinoma of the head and neck Cancer 119

Version of Record online: 18 SEP 2012 | DOI: 10.1002/cncr.27741

Induction chemotherapy with nab-paclitaxel and cetuximab given with cisplatin and 5-fluorouracil resulted in a high complete response rate (53%) at the primary tumor site, even in large tumors, and did not adversely affect delivery of definitive chemoradiation. Two-year survival outcomes with this regimen were very favorable.

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