Marica Gemei, Peppino Mirabelli, Rosa Di Noto, Claudia Corbo, Antonino Iaccarino, Anna Zamboli, Giancarlo Troncone, Gennaro Galizia, Eva Lieto, Luigi Del Vecchio and Francesco Salvatore CD66c is a novel marker for colorectal cancer stem cell isolation, and its silencing halts tumor growth in vivo Cancer 119
Article first published online: 1 OCT 2012 | DOI: 10.1002/cncr.27794
Cluster of differentiation 66c (CD66c) (also known as carcinoembryonic antigen-related cell adhesion molecule 6) is specifically expressed by colorectal cancer stem cells compared with normal colon stem cells. This new marker has several functional implications in tumor growth and progression.
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