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Vikas Sehdev, Ahmed Katsha, Jeffrey Ecsedy, Alexander Zaika, Abbes Belkhiri and Wael El-Rifai The combination of alisertib, an investigational Aurora kinase A inhibitor, and docetaxel promotes cell death and reduces tumor growth in preclinical cell models of upper gastrointestinal adenocarcinomas Cancer 119

Version of Record online: 12 SEP 2012 | DOI: 10.1002/cncr.27801

The combination of alisertib and docetaxel exhibits enhanced anticancer potency in upper gastrointestinal adenocarcinomas both in vitro and in vivo. Therefore, the alisertib and docetaxel combination can mediate a better therapeutic outcome in patients with gastrointestinal cancers.

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