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Radka Stoyanova, Niraj H. Pahlajani, Brian L. Egleston, Mark K. Buyyounouski, David Y. T. Chen, Eric M. Horwitz and Alan Pollack The impact of dose-escalated radiotherapy plus androgen deprivation for prostate cancer using 2 linked nomograms Cancer 119

Version of Record online: 23 OCT 2012 | DOI: 10.1002/cncr.27857

There are no published randomized trials that address the impact of adding androgen-deprivation therapy (ADT) to dose-escalated, definitive radiotherapy (RT). Dual-linked nomograms that were developed by the authors allow for estimates of the effects of different lengths of ADT on the outcome of patients who receive different RT doses. The results indicate that adding ADT is more important than a modest RT dose escalation.

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