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Kin-Fai Cheung, Junhong Zhao, Ying Hao, Xiaoxing Li, Anson W. Lowe, Alfred S. L. Cheng, Joseph J. Y. Sung and Jun Yu CITED2 is a novel direct effector of peroxisome proliferator-activated receptor γ in suppressing hepatocellular carcinoma cell growth Cancer 119

Article first published online: 4 DEC 2012 | DOI: 10.1002/cncr.27865

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (CITED2) is a novel direct effector of peroxisome proliferator-activated receptor γ and plays a critical role in hepatocellular carcinoma as a potential tumor suppressor through regulating cell proliferation and cell cycle progression. These results provide new mechanistic insight into the antitumor effect of peroxisome proliferator-activated receptor γ.

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