Tamar Tadmor, Lev Shvidel, Ariel Aviv, Rosa Ruchlemer, Osnat Bairey, Mona Yuklea, Yair Herishanu, Andre Braester, Naomi Levene, Fiona Vernea, Jonathan Ben-Ezra, Jacob Bejar, Aaron Polliack and on behalf of the Israeli CLL Study Group Significance of bone marrow reticulin fibrosis in chronic lymphocytic leukemia at diagnosis Cancer 119
Version of Record online: 19 FEB 2013 | DOI: 10.1002/cncr.27930
This study demonstrates a significant correlation between the grade of reticulin fibrosis of the bone marrow and poor overall survival and outcome in patients with chronic lymphocytic leukemia (CLL). This easy staining procedure can readily be added routinely when examining bone marrow biopsies in CLL, because results have prognostic implications for patients with CLL.
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