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Eunju Lee, Bo Bin Lee, Eunkyung Ko, Yujin Kim, Jungho Han, Young Mog Shim, Joobae Park and Duk-Hwan Kim Cohypermethylation of p14 in combination with CADM1 or DCC as a recurrence-related prognostic indicator in stage I esophageal squamous cell carcinoma Cancer 119

Version of Record online: 10 JAN 2013 | DOI: 10.1002/cncr.27948

Despite significant advances in the detection and treatment of esophageal cancer, the prognosis for patients with the disease is very poor, which results in part from the high rate of recurrence. This study indicates that the analysis of methylation statuses of the genes cyclin-dependent kinase inhibitor 2A (p14), cell adhesion molecule 1 (CADM1), and deleted in colon carcinoma (DCC) in patients with stage I esophageal squamous cell carcinoma will allow the identification of patients who are at high risk of recurrence after esophagectomy.

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