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Wayne T. Lin, Mary Beattie, Lee-may Chen, Kutluk Oktay, Sybil L. Crawford, Ellen B. Gold, Marcelle Cedars and Mitchell Rosen Comparison of age at natural menopause in BRCA1/2 mutation carriers with a non–clinic-based sample of women in northern California Cancer 119

Article first published online: 29 JAN 2013 | DOI: 10.1002/cncr.27952

Carriers of BRCA1 and BRCA2 (BRCA1/2) mutation tend to undergo earlier natural menopause compared with the general population, and current heavy smoking is associated with the onset of menopause at an even earlier age. To the authors' knowledge, this is the first study to explore the association between BRCA1/2 and age at the onset of menopause by comparing BRCA1/2 carriers with women in the general population.

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