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Hui Xie, Xifeng Wu, Shui Wang, David Chang, Raphael E. Pollock, Dina Lev and Jian Gu Long telomeres in peripheral blood leukocytes are associated with an increased risk of soft tissue sarcoma Cancer 119

Version of Record online: 13 FEB 2013 | DOI: 10.1002/cncr.27984

This is the first epidemiological study to evaluate constitutive telomere length with the risk of soft tissue sarcoma (STS). The results indicate that longer telomere length in peripheral blood lymphocytes is associated with an increased risk of STS with a significant dose-response effect, suggesting differential roles of telomere dysfunction in sarcoma and epithelial tumor development.

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