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Kunal S. Jain, Andrew G. Sikora, Shrujal S. Baxi and Luc G. T. Morris Synchronous cancers in patients with head and neck cancer Cancer 119

Version of Record online: 19 FEB 2013 | DOI: 10.1002/cncr.27988

This population-based cohort study, which was performed using Surveillance, Epidemiology, and End Results (SEER) data, demonstrates the various risks of synchronous second cancers among patients with head and neck cancer and the dramatic decrease in risk among patients with oropharyngeal cancer since the 1990s. These data are consistent with the etiologic shift of oropharyngeal squamous cell carcinoma from a primarily tobacco-based malignancy to a disease caused by oncogenic human papillomavirus.

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