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Sai Yendamuri, Miriam Huang, Usha Malhotra, Graham W. Warren, Paul N. Bogner, Chukwumere E. Nwogu, Adrienne Groman and Todd L. Demmy Prognostic implications of signet ring cell histology in esophageal adenocarcinoma Cancer 119

Version of Record online: 29 MAY 2013 | DOI: 10.1002/cncr.28099

The prognostic role of signet ring cell histology in esophageal cancer is unclear; only a few reports of single-institution series with inconclusive results have been published. In this study, the authors have used the large numbers of patients in the Surveillance, Epidemiology, and End Results (SEER) database to establish the negative prognosis associated with this uncommon variant of esophageal adenocarcinoma.

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