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Smith Apisarnthanarax, Samuel Swisher-McClure, Wing K. Chiu, Randall J. Kimple, Stephen L. Harris, David E. Morris and Joel E. Tepper Applicability of randomized trials in radiation oncology to standard clinical practice Cancer 119

Article first published online: 14 MAY 2013 | DOI: 10.1002/cncr.28149

A significant proportion of medical decisions are made without available or applicable randomized evidence to inform radiotherapeutic medical decision making in an academic radiation oncology clinic. These findings underscore the limitations of relying solely on prospective randomized controlled trials for the development of evidence-based health care.

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