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Rainer Fietkau, Victor Lewitzki, Thomas Kuhnt, Tobias Hölscher, Clemens-F. Hess, Bernhard Berger, Thomas Wiegel, Claus Rödel, Marcus Niewald, Robert M. Hermann and Dorota Lubgan A disease-specific enteral nutrition formula improves nutritional status and functional performance in patients with head and neck and esophageal cancer undergoing chemoradiotherapy: Results of a randomized, controlled, multicenter trial Cancer 119

Version of Record online: 13 JUN 2013 | DOI: 10.1002/cncr.28197

Enteral nutrition with a metabolically adapted cancer-specific enteral formula high in protein and eicosapentaenoic acid (EPA) may be advantageous in patients with head and neck or esophageal cancer, improving parameters of nutritional and functional status during chemoradiotherapy. These beneficial effects may be related to the provision of EPA and to the specific nutrient profile adapted to the tumor-induced alterations in substrate metabolism by increasing the fat/carbohydrate ratio.

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