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Timothy J. Daskivich, Karim Chamie, Lorna Kwan, Atreya Dash, Sheldon Greenfield and Mark S. Litwin Matching tumor risk with aggressiveness of treatment in men with multiple comorbidities and early-stage prostate cancer Cancer 119

Article first published online: 16 JUL 2013 | DOI: 10.1002/cncr.28226

Men with multiple comorbidities tended to have lower probability of aggressive treatment for high-risk disease than other tumor risk strata, despite a strong trend toward survival advantage with aggressive treatment of high-risk disease (but not low- or intermediate-risk disease). Men with major comorbidities should consider conservative management for low- and intermediate-risk disease and aggressive treatment for high-risk disease.

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